With so many different fertility monitors on the market, it can be hard to decide which is the right monitor for you. Different methods are used to determine your fertile window and increase your chances at conception. It is important to understand exactly how the monitor is predicting your ovulation and the accuracy of these results. Accuracy, ease of use, and having ample notice of ovulation are important considerations and the reason we believe the Ovacue Fertility Monitor to be the optimal choice. Here’s a breakdown of the competition:

Urine-based monitors uses LH and estradiol to predict peak fertility and ovulation. With notice only a day before ovulation and the day of ovulation on average, it provides little advance notice. Urine-based monitors are designed to detect ovulation due to a pre-determined level of estrogen (E3G) in the urine. As all women are different, this is less accurate for those not at that pre-determined level. On top of the cost for the monitor, additional test sticks are needed and must be purchased continually for use with these monitors.

Basal Body Temperature charting is an older approach to track your ovulation. Charting your basal body temperature is useful only to confirm ovulation, not for prediction of your fertile window. It can be used to notice trends and patterns in your cycle if you happen to have a regular cycle. Once you notice a temperature rise, ovulation has happened and it is too late to conceive. This method was used before products such as the OvaCue Fertility Monitor were developed.

Similar to the use of basal body temperature, using LH urine sticks once again gives little to no advance notice of your fertile window. The LH surge first peaks in your blood and then travels into your urine, leaving little time to determine your fertile window and time intercourse appropriately. It can require testing multiple times a day to catch the LH surge and even with a positive result, it may be difficult to interpret.

The following provides a brief comparison of Zetek's Electrolyte Method™ embodied in the OvaCue® Fertility Monitor, with that of urine-based electronic fertility monitors. Zetek's Electrolyte Method relies on changes in the electrolytes in saliva to predict ovulation (the key indicator of fertility) up to seven days in advance. Changes in the electrolytes in vaginal mucus are monitored by the OvaCue to confirm ovulation. Comparisons can be grouped into the following categories:

The "fertile window" is defined as the days in a woman's cycle in which she can actually conceive. For this evaluation, we use the definition of the "fertile window" from Wilcox, et al.1, i.e., the day of ovulation and the five days just preceding it, as well as the same authors' conclusion that the urinary leutinizing hormone (uLH) tests are positive on the day of, not the day before, ovulation.

Urine-based electronic monitors are based on detection of a pre-determined level of estrogen (E3G) in the urine. In a study of one such monitor, details are described in their physicians' manual. Per their literature, in 352 cycles, this level of estrogen was detected before the "fertile window" 13% of the time. It was not seen until after the actual day of ovulation in 14% of the cycles. For the remaining 73% of cycles, the fertile signals happened within the fertile window, where "...the mean location of the first High Fertility day was 3.01+/- 2.33 days before the fertility monitor identified the [urine] LH surge..."2, a very wide standard deviation. This means that this urine-based monitor accurately identifies fertile days within the fertile window only 73% of the time. The uLH positive signal is most frequently seen on the day of ovulation. Urine-based monitors use this signal as the start of 3 "peak" days, even though at least one, and usually 2 or 3 of these "peak" days are after the fertile window has closed when it is too late to achieve conception. In Zetek's NIH Phase II3 study, using various uLH tests, the uLH threshold for a positive reading was not reached at all in 24% (72 of 300) of the cycles tested, which demonstrates the fact that the uLH used with urine-based methods is not as useful as a predictor of ovulation. OvaCue vaginal readings indicate the response of the vaginal mucus to estrogen and progesterone, rather than directly to LH. The nadir of OvaCue readings is associated with the preovulatory peak in estrogens. The rise immediately thereafter signals the shift from estrogen to progesterone dominance. The rise in OvaCue vaginal readings thus occurs on the day of the serum (blood) LH peak, or about 12 hours before the detection of the uLH signal. In conclusion, it seems that by using uLH, urine-based monitors miss defining the fertile window accurately in a significant number of cases, while Zetek's Electrolyte Method more accurately defines the fertile window, and thus a woman's peak fertility.

OvaCue offers a significant consumer advantage, when compared to urine-based monitors, in that inconvenient or unsanitary urine handling is not required. The OvaCue simply requires that a teaspoon-shaped oral sensor be placed on the tongue for 3 seconds every morning. The monitor stores those readings and automatically computes a woman's fertility status for any day of the present cycle. A vaginal sensor may also be used for about 5 days of the fertile window to confirm ovulation. Vaginal readings also are completed in 3 seconds, in addition to the brief time necessary to prepare for the reading. Because both sensors are sealed (water-tight) and not exposed to urine, they can be easily cleaned and prepared for the next day's reading, with little or no inconvenience.

The retail price of the OvaCue is €249. The retail price of urine-based monitors ranges from €189 - €229. However, these monitors also require that additional test sticks be purchased at a cost of €40 - €50 per cycle. Therefore, within 2 months urine-based monitors become more expensive, with the cost rising with each purchase of test sticks. OvaCue sensors are sealed and sterilized before shipping, and can be cleaned with mild detergents or Isopropyl Alcohol. Because the OvaCue can be used effectively for years with nothing more to buy, it provides a substantial cost savings when compared to the annual cost of urine-based monitors which can add over $400 per year to the actual monitor unit cost.

Advance notice of ovulation is crucial for monitoring fertility, independently of a consumer's particular fertility goals. For avoiding pregnancy, a couple must know well in advance when ovulation will occur, so that they may abstain during all six days of the fertile window4. For couples seeking to achieve pregnancy, advance notice is important to plan for the timing of intercourse or for the scheduling of in-vitro fertilization or artificial insemination. The OvaCue offers a significant advantage by giving up to 7 days advance notice of ovulation, more than any other ovulation prediction method.

All customers of OvaCue are welcome to call a toll-free helpline at any time during the first year of use of the OvaCue. Questions about the specific use of the monitor or general questions about fertility and reproductive science are answered by experienced staff at no cost to the consumer. OvaCue's trained fertility experts also are available to help track a woman's cycle and to identify the proper time for her to attempt conception. No urine-based monitors offer support of this nature.

OvaCue has been helping couples meet their fertility goals since 1983. For almost 20 years, OvaCue has pioneered the way in electronic ovulation prediction and fertility monitors. Over 17 articles about OvaCue and the Electrolyte Method have been published in noted scientific and peer-reviewed journals, and over 2,000 cycles of OvaCue data have been collected and analyzed. These articles document extensive independent scientific research conducted with OvaCu's methodology. Also during that period, two NIH funded studies were completed at the University of Colorado Health Sciences Center, which proved the efficacy of OvaCue's method and determined that the OvaCue is 98% accurate in predicting and confirming ovulation, i.e., determining the optimum time for intercourse or insemination.

The OvaCue and the Electrolyte Method have been approved for use as an aid to conception by the U.S. FDA. The method and device have also been approved by the Vatican as consistent with the teachings of the Catholic Church and finally, the Electrolyte Method has been recommended by numerous doctors specialized in the field of reproductive medicine. The OvaCue has also been recommended by thousands of couples that conceived using the OvaCue when they were unable to conceive using other methods.

The OvaCue has numerous practical and scientific advantages over urine-based electronic fertility monitors. OvaCue's method also has numerous advantages over any other existing method of predicting or confirming ovulation.